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In severe cases, subacute combined degeneration of the spinal cord can occur, affecting both sensory and motor function
Nature , 508(7495), 258262
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Given the unlicensed status of retatrutide in the UK and the complexity of injectable peptide reconstitution, seeking qualified medical advice before any use is strongly recommended and in many circumstances, essential
Licensed pharmacological options such as orlistat and semaglutide (Wegovy, per NICE TA875) may be appropriate for eligible individuals
Chronic C75 treatment of diet-induced obese mice increases fat oxidation and reduces food intake to reduce adipose mass
No lethal dose was reached in preclinical toxicology studies, and no significant adverse effects have been reported in published research
